Proteintech, 80837-1-RR-20ul, ALDOA Recombinant monoclonal antibody

80837-1-RR targets ALDOA in WB, IF/ICC, ELISA applications and shows reactivity with Human, Mouse, Pig, rat samples.
Tested Applications
Positive WB detected in: HeLa cells, HEK-293 cells, HepG2 cells, Jurkat cells, NIH/3T3 cells, 4T1 cells, HSC-T6 cells, pig liver tissue, pig skeletal muscle tissue
Positive IF/ICC detected in: HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:5000
Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500
Background Information
ALDOA(Fructose-bisphosphate aldolase A) is also named as lung cancer antigen NY-LU-1,muscle-type aldolase,ALDA and belongs to the class I fructose-bisphosphate aldolase family.The ALDOA gene encodes a homotetrameric protein(PMID:14615364).It is found in skeletal muscle and red blood cells, and functions in glycolysis, promoting the reversible cleavage of FBP to triose phosphate, G-3-P and DHAP. ALDOA is upregulated in various cancers, including human lung squamous and renal cell carcinomas(PMID:19937139).