Description
83026-5-RR targets ACVR1B in IF/ICC, FC (Intra), ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive IF/ICC detected in: NIH/3T3 cells
Positive FC (Intra) detected in: HEK-293 cells
Recommended dilution
Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500
Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
ACVR1B (ALK4, activin A receptor type 1B) is a transforming growth factor-beta (TGF-beta) superfamily member (PMID: 37020544). A potential role for ACVR1B in regulating muscle mass is that it is part of the transforming growth factor b (TGFb) pathway regulating myostatin (PMID: 21063444).