Description
84546-2-RR targets ADH1C in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: mouse liver tissue, mouse colon tissue, human kidney tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
Alcohol dehydrogenase 1C(ADH1C), also known as ADH3, is an alcohol dehydrogenase that can catalyze ethanol oxidation to metabolite acetaldehyde. According to THE HUMAN PROTEIN ATLAS database, ADH1C locates mainly to the cytosol and plasma membrane. Genetic polymorphism of the ADH1C gene (ADH1C*1 allele) is associated with various human cancers, such as gastric cancer, oral cancer and CRC, for it encodes an alcohol dehydrogenase producing 2.5 times more acetaldehyde.(PMID: 35300114)