Description
85349-1-RR targets AGER/RAGE in WB, ELISA applications and shows reactivity with human, mouse, pig samples.
Tested Applications
Positive WB detected in: mouse lung tissue, pig lung tissue
Recommended dilution
Western Blot (WB): WB : 1:2500-1:10000
Background Information
The receptor for advanced glycation end products (RAGE) is a cell surface transmembrane multiligand receptor, also known as Ager, is a multiligand member of the immunoglobulin superfamily. It has many isoforms and is predominantly expressed in the lung. AGER expression is upregulated in many diseases such as Alzheimer's disease, diabetes mellitus, atherosclerosis, and rheumatoid arthritis (PMID: 35099614).