Proteintech, 85769-4-RR-100ul, AKT3 Recombinant monoclonal antibody

85769-4-RR targets AKT3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: SH-SY5Y cells, mouse brain tissue, rat brain tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
AKT3, also named as PKBG, is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT3 is a key modulator of several tumors like melanoma, glioma and ovarian cancer. Active AKT3 increases progressively during melanoma tumor progression with highest levels present in advanced-stage metastatic melanomas.