Proteintech, 86131-1-RR-20ul, ADSL Recombinant monoclonal antibody

86131-1-RR targets ADSL in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HL-60 cells, Ramos cells, NIH/3T3 cells, C6 cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:10000
Background Information
Adenylosuccinate lyase (ADSL) is an essential enzyme for de novo purine biosynthesis and the purine nucleotide cycle, where it plays a key role in the regulation of adenosine monophosphate levels in the cells. Given its crucial role in both cellular replication and metabolism, it is not surprising that ADSL has been found dysregulated in several malignancies, including breast and endometrial cancers as well as glioma. (PMID: 33754045)