Description
86297-1-RR targets ALDH4A1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HepG2 cells, K-562 cells, A549 cells, BT-474 cells, mouse skeletal muscle tissue, rat skeletal muscle tissue, human skeletal muscle tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
ALDH4A1(Aldehyde dehydrogenase family 4 member A1) is also named as ALDH4, P5CDH,P5C dehydrogenase and belongs to the aldehyde dehydrogenase family. P5CDH is a mitochondrial matrix NAD(+)-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Defects in ALDH4A1 are the cause of hyperprolinemia type 2 (HP-2).