Description
86519-4-RR targets ABCD2 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse cerebellum tissue, mouse adipose tissue, rat cerebellum tissue
Positive IP detected in: mouse cerebellum tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Background Information
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters, and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. ABCD2 plays a role in regulation of VLCFAs and energy metabolism, in the degradation and biosynthesis of fatty acids by beta-oxidation (PMID:29397936, 21145416).