Description
86988-1-RR targets AKTIP in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: MDA-MB-231 cells, MCF-7 cells, HepG2 cells, U-251 cells, NIH/3T3 cells, mouse heart tissue, rat heart tissue
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
AKTIP is a telomeric protein with the property of being enriched at the nuclear lamina. AKTIP has similarity with the tumor susceptibility gene TSG101. AKTIP deficiency generates genome instability and, in p53−/− mice, the reduction of the mouse counterpart of AKTIP induces the exacerbation of lymphomas.