Description
The DML 3000 instrument is a luminometer that automates amplified chemiluminescent signal detection and results reporting for HC2 assays, including the digene HC2 High-Risk HPV DNA Test.
The DML instrument is a benchtop, computer-controlled instrument designed for measuring and analyzing light produced by the glow-type chemiluminescence used in HC2 technology. The DML instrument measures light in the visible spectrum (300–650 nm) and measures chemiluninescence from opaque microplates. Performance specifications of the DML 3000 Performance measure Specification Spectral sensitivity range 350–650 nm Dynamic range 10 to 5 x 10 6 RLU Cross-talk Less than 4.0 x 10 –5 RLU
Hybrid Capture 2 technology detects RNA–DNA hybrids using signal-amplified chemiluminescent techology. HC2 technology delivers the accuracy and flexibility necessary for routine detection of DNA that can assist in the diagnosis of infectious diseases. The DML instruments automate the signal detection and results reporting for HC2 assays.
Once a microplate has been processed manually or using the Rapid Capture System (RCS), the microplate is loaded at the front of the DML instrument. The individual microplate wells are sequentially moved beneath the opening of the detector and individually measured. The digene HC2 System Software provides data reduction and works in conjunction with the DML instrument to report final results. The software interface between the digene HC2 System Software and the Laboratory Information System (LIS) can be programmed to transmit data into reportable results by a testing laboratory.
