Description
CIMac Analytical Columns are intended for fast and reproducible HPLC monitoring and quantitation of large proteins, plasmid DNA, viruses, virus-like particles, and phages. They were primarily designed for the in-process and final control of various samples at different stages of the purification process. They can be operated at high volumetric flow rates (from 1 to 20 column volumes/min); therefore, the information about the product quantity and purity can be obtained within a few minutes. CIMac Analytical Columns are fast and reliable PAT tools, providing:
Rapid, high resolution analysis, achieved in minutes
Flow independent separation
High sensitivity and reproducibility
QA (quaternary amine) features:
Strong anion exchanger
Working range, pH 2–13
Binds molecules with predominantly negative charge, repels molecules with a predominantly positive charge
Use for capture, intermediate, or polishing steps in either bind-elute or flow-through mode
High capacity for virus particles, IgM, exosomes
High efficiency removal of endotoxin and DNA removal
Outstanding for preparative applications or analytical finger-printing of process samples
Sanitizable with 1 M NaOH
