Description
The cGMP In-line Lysis Tower 5000 serves as the controller unit in the system with user-friendly software. It contains four peristaltic pumps precisely controlled via ultrasonic flow sensors, ensuring tight control over process conditions. The System’s Tower also contains all safety precautions, such as non-contact pressure sensors, to allow for safe process execution.
Operating Flow Rate: 40 -1000 mL/min
Compatible with:
Single Use Lysis Reactor 1000 mL
Single Use GMP Lysis Reactor 1000 mL
Single Use Lysis Reactor 5000 mL
Single Use GMP Lysis Reactor 5000 mL
Key Benefits:
Continuous process, that can be coupled with filtration and capture.
Can process up to 500 L of resuspended cells in 8h.
State-of-the-art mixing control (low shear mixing).
Offers precise control over NaOH exposure during cell lysis with efficient neutralisation and controlled cell debris precipitation.
No need for chilled reagents.
Improved robustness and contaminant removal (genomic DNA, isoform homogeneity).
Efficient separation of debris from lysate, increasing the life span of filters used in next steps.
Operating protocol is easily transferable from batch mode to the Sartorius In-line System.
Low space requirements.
cGMP compliant.
