Stemcell, 05160, STEMdiff™ Kidney Organoid Kit

STEMdiff™ Kidney Organoid Kit is a complete, serum-free cell culture medium system that supports highly efficient and reproducible generation of human pluripotent stem cell (hPSC)-derived kidney organoids in a simple, two-stage differentiation protocol. These kidney organoids are composed of podocytes, proximal tubules, distal tubules, as well as the associated endothelium and mesenchyme.

Kidney organoids generated with STEMdiff™ Kidney Organoid Kit are tested for compatibility with phenotypic high-throughput assays such as nephrotoxic compound screening. They also provide a relevant and convenient model for studies related to developmental biology and disease modeling.

The kit has been optimized for the differentiation of hPSCs previously cultured in mTeSR1 (Catalog #85850). It is also compatible with mTeSR Plus (Catalog #100-0276) maintained hPSCs, provided that mTeSR1 medium is used for the first three days of the protocol.