Stemcell, 100-0244, Dibutyryl-cAMP

Name: Dibutyryl-cAMP
Brand: Stemcell
SKU: 100-0244

Size: 250 mg, cAMP pathway activator; Activates cAMP-dependent protein kinases

Catalog Number: 100-0244

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Category

Differentiation Media

Pack Size250 mg

TagsProduct Portfolios Differentiation Neural Stem and Progenitor Cell Research

Description

Dibutyryl-cAMP is a cell-permeable cyclic AMP (cAMP) analog that activates cAMP-dependent protein kinases (Schwede et al.). This product is supplied as the sodium salt of the molecule.

DIFFERENTIATION

· Suppresses experimental autoimmune encephalomyelitis development by reducing demyelination and mobilizing neural stem cells in the subventricular zone towards the demyelinated plaques (Khezri et al.).

· Induces intrinsic axon growth in peripheral and central nervous systems, and morphological differentiation of astrocytes (Knott et al.; Imamura & Ozawa).

· Stimulates neurite outgrowth in PC12 cells (Maruoka et al.).

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Stemcell, 100-0244, Dibutyryl-cAMP

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