Stemcell, 100-0383, HepatiCult™ Organoid Differentiation Medium (Human)

Reliably generate mature human liver organoids that demonstrate hepatic functionality with HepatiCult™ Organoid Differentiation Medium (ODM) (Human), which includes all components required to support robust differentiation of hepatic organoids derived from fresh or cryopreserved human liver tissue.

Available either individually or as part of HepatiCult™ Organoid Kit (Human), HepatiCult™ ODM can be used to differentiate organoids initiated in HepatiCult™ Organoid Initiation Medium (Human) and/or expanded in HepatiCult™ Organoid Growth Medium (Human). Organoids differentiated with HepatiCult™ ODM express hepatocyte markers (ALB, CYP3A4, MRP4) and exhibit upregulated albumin secretion and CYP3A4 activity relative to undifferentiated organoids. These organoids can be adapted to a range of culture protocols, including suspension cultures and high-throughput assays.

For more information on protocols for organoid culture with HepatiCult™, please explore the Technical Manual and Educational Materials.

Should you intend to use this product for commercial purposes, please contact HUB at www.huborganoids.nl for a commercial use license or for clarifications in relation to HUB licensing.