Stemcell, 100-1068, Anti-Human Lysozyme Antibody, Polyclonal

This rabbit polyclonal antibody reacts with human lysozyme, a secreted protein found in high concentration in various tissues and fluids, such as in liver, articular cartilage, saliva, and tears. Use this polyclonal antibody in applications requiring lysozyme detection, such as immunohistochemistry protocols (IHC-P). It has been verified for use with immunocytochemistry (ICC).

Lysozyme performs bacteriolytic functions, hydrolyzing the β-1,4 glycosidic linkages that are found on the peptidoglycan cell walls of various bacteria. Lysozyme also plays an important role in the modulation of pro-inflammatory immune responses. Particularly, the lysozyme-catalyzed degradation of bacteria results in inflammasome activation and macrophage recruitment through cytosolic receptors, like NOD1 and NOD2. In addition to its importance in driving a pro-inflammatory response, lysozyme also plays a role in limiting inflammation by reducing AGE-induced IL-6 production.