Stemcell, 100-1128, L-Cysteine

Regulate cell signaling pathways and support protein synthesis with L-Cysteine, a semi-essential amino acid found in high-protein foods (Yin et al.). Additionally, L-cysteine has been shown to enhance papain activity (Homaei et al.).

L-Cysteine has been used for:

DISEASE MODELING

· Increases insulin sensitivity by upregulating glutathione (GSH) and adiponectin in 3T3-L1 adipocyte model (Achari and Jain).

· Restores cellular glutathione and inhibits the expression of cell adhesion molecules in G6PD-deficient human U937 monocytes (Parsanathan and Jain SK.).

· Promotes the conversion of microglia from an inflammatory M1 to an anti-inflammatory M2 phenotype in mouse ischemia-hypoxia models. L-cysteine suppressed the production of inflammatory cytokines, while upregulating anti-inflammatory cytokines in the damaged mouse cortex. L-cysteine also inhibited neuronal cell apoptosis induced by conditioned medium from activated M1 microglia in vitro (Zhou et al.).