Stemcell, 72332, UM729

Name: UM729
Brand: Stemcell
SKU: 72332

Size: 250 µg, Pyrimido-indole derivative that enhances HSC self-renewal in vitro

Catalog Number: 72332

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Category

Hematopoietic Stem Cell Media

Pack Size250 µg

TagsProduct Portfolios Hematopoietic Cell Therapy Development View All

Description

UM729 is a pyrimido-[4,5-b]-indole derivative which enhances the self-renewal of human hematopoietic stem cells in vitro. UM729 does not inhibit the aryl hydrocarbon receptor (AHR) pathway, but has been shown to collaborate with AHR antagonists in preventing differentiation of acute myeloid leukemia (AML) cells in culture.

MAINTENANCE AND SELF-RENEWAL

· Enhances human hematopoietic stem cell self-renewal in vitro (Fares et al.).

CANCER RESEARCH:

· Collaborates with StemRegenin 1 (SR1) in preventing differentiation of AML cells in culture (Pabst et al.).

For clinical use of UM729, please contact ExCellThera.

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