Stemcell, 72602, OAC1

Name: OAC1
Brand: Stemcell
SKU: 72602

Size: 5 mg, Inducer of OCT4 expression

Catalog Number: 72602

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Category

Insect Cell Expression Systems

Pack Size5 mg

TagsProduct Portfolios Mouse Pluripotent Stem Cell Research Reprogramming

Description

OAC1 is an OCT-4-activating compound that activates expression through the OCT-4 gene promoter (Li et al.). Oct-4 (POU5F1) is a transcription factor that is critically involved in the self-renewal of pluripotent stem cells, and its expression is commonly used as a marker for pluripotency.

REPROGRAMMING

· Enhances the reprogramming efficiency of mouse embryonic fibroblasts transfected with OCT4, SOX2, KLF4, and c-MYC (Li et al.).

MAINTENANCE AND SELF-RENEWAL

· Mediates ex vivo expansion of cord blood CD34+ hematopoietic stem and progenitor cells (Huang et al.).

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Stemcell, 72602, OAC1

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