Stemcell, 74242, Bafilomycin A1

Name: Bafilomycin A1
Brand: Stemcell
SKU: 74242

Size: 500 µg, Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

Catalog Number: 74242

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Category

Small Molecule Inhibitors for Stem Cells

Pack Size500 µg

TagsProduct Types Small Molecules

Description

Bafilomycin A1 is a macrolide antibiotic drug and autophagy inhibitor. It prevents the acidification of autophagosomes via the inhibition of vacuolar H+-ATPase (V-ATPase; Klionsky et al.).

MAINTENANCE AND SELF-RENEWAL

· Inhibits the proteolytic degradation associated with autophagy in human mesenchymal stem cells (Oliver et al.).

CANCER RESEARCH

· At low concentrations, it inhibits autophagy and promotes apoptotic cell death in pediatric B cell acute lymphoblastic leukemia (B-ALL) cells (Yuan et al.).

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Stemcell, 74242, Bafilomycin A1

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