Description
Quantity: 500 μg
Unit Size: Each
The CaptureSelect Biotin Anti-LC-kappa (Hu) Conjugate allows you to:
• Detect, quantitate, and characterizeall human antibody isotypes and subclasses (for example, IgG1 to 4, IgM, IgA, IgD, and IgE), and Fab fragments thereof, that contain a kappa light chain; as well as recombinant human Fab fragments and/or Fab and Fab2 fragments obtained after papain or pepsin digestion
• Avoid cross-bindingwith human antibodies that possess a lambda light chain or IgG from bovine sources such as FCS
• Screen antibody-antigen interactions—biotin anti-LC-kappa (Hu) forms a stable [low k(diss)] complex with, for example, human IgG antibodies through bivalent bindingApplications for CaptureSelect Biotin Anti-LC-kappa (Hu) Conjugate include ELISA, Western blot, Gyrolab™-based immunoassays, and label-free detection platforms such as those based on surface plasmon resonance (Biacore™ and IBIS-MX96 systems) and bio-layer interferometry (ForteBio™ Octet™ systems).Free of animal componentsCaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
