Description
Description: Immunofluorescent assay for quantitative determination of soluble chromogranin A (CgA)
For Use With (Application): The B·R·A·H·M·S CgA II KRYPTOR test is indicated as an aid to be used in conjunction with clinical evaluation for follow-up and monitoring of patients with neuroendocrine tumors (NETs) and for therapy monitoring of patients with prostate cancer. The test is further indicated as an aid to be used in conjunction with clinical evaluation for the diagnosis of patients with suspected pheochromocytomas. Please consult IFU available in your country.
Unit Size: Pack of 50
• Chromogranin A is an acidic, hydrophilic protein of 49 kDa present in chromaffin granules of the neuroendocrine cells and is a member of the granin family.
• Neuroendocrine tumors (NETs) originate from neuroendocrine cells found in neuronal and endocrine tissues throughout the body.
• The most common sites of NETs are the lung, stomach, appendix, cecum, duodenum, pancreas, jejunum/ileum, colon and rectum.
• NETs arising from the gastrointestinal tract are collectively known as gastroentero-pancreatic neuroendocrine tumors.
• Follow up and monitoring investigations of NETs are based on tumor markers together with other diagnostic measures and clinical signs.
• Besides its use as immunohistological marker, CgA has been well recognized as a general broad-spectrum serum marker in GEP-NETs.
