Thermo Fisher, J63397.MD, Geldanamycin, 98+%

Name: Geldanamycin, 98+%
Brand: Thermo Fisher
SKU: J63397.MD

Quantity: 250 mg, Unit Size: Each, Geldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio.

Catalog Number: J63397.MD

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Category

Protein-Free Media

Pack Size250 mg

TagsCell Culture Media Antibiotics Supplements and Reagents Cell Culture Reagents Antibiotics and Supplements

CollectionsThermo Fisher Cell Culture Media & Supplements | Serum-Free, Chemically Defined Thermo Fisher Clinical Analyzers & Instruments for Diagnostic Labs Thermo Fisher General Lab Supplies for Daily Workflows — Nalgene, Nunc, Samco & Matrix

Description

Quantity: 250 mg
Unit Size: Each
ApplicationsGeldanamycin binds to and inhibits the cytosolic chaperone functions of heat shock protein 90 (HSP90). HSP90 maintains the stability and functional shape of many oncogenic signaling proteins. It interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.SolubilitySoluble in dimethyl sulfoxide at 100 mg/mL.NotesStore in a cool dry place. Keep away from oxidizing agents. Protect from heat.

Specifications

General

CAS	30562-34-6
Chemical Name or Material	Geldanamycin
Formula Weight	560.64
IUPAC Name	[(3S,5R,6S,7R,8Z,11R,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate
InChI Key	QTQAWLPCGQOSGP-KDFVLELPSA-N
MDL Number	MFCD00274570
Molecular Formula	C29H40N2O9
PubChem CID	133688416
RTECS Number	LX8920000
Recommended Storage	Store at -20°C
SMILES	CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)C)OC)OC(=O)N)C)C)O)OC
Solubility Information	Soluble in dimethyl sulfoxide at 100mg/mL.
Synonym	NSC 122750; U-29135
TSCA	No
Color	Orange to Yellow
Molecular Weight (g/mol)	560.644
Percent Purity	≥99%
Physical Form	Powder
Quantity	250 mg
Type	Geldanamycin
Unit Size	Each

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Thermo Fisher, J63397.MD, Geldanamycin, 98+%

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