Thermo Fisher, TS-48915, MSTFA and MSTFA + 1% TMCS Silylation Reagent

Standard Components: MSTFA + 1% TMCS
Quantity: 10 x 1 mL ampules
Unit Size: Each
• Trimethylsilyl donor strength comparable to BSA and BSTFA
• Reacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH_3)_3group
• Used to prepare volatile and thermally stable derivatives for GC and MS
• Volatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFA
• Often TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
• Addition of Thermo Scientfic TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone