AQ12S05-2546WT, YMC-Pack ODS-AQ

Name: YMC-Pack ODS-AQ
Brand: YMC
SKU: AQ12S05-2546WT

column

Catalog Number: AQ12S05-2546WT

Pricing

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Category

Size Exclusion HPLC Columns

TagsC18

Description

Classical polar phase.
YMC-Pack ODS-AQ is a unique reversed-phase material with both a hydrophobic high carbon loading and a relatively hydrophilic surface. Because of the hydrophilic surface, ODS-AQ can be “wetted” with polar eluents. It provides chromatographers reproducible retention and excellent peak shape in highly aqueous mobile phases including 100% water. This is due to the C18 ligands on ODS-AQ actually being lifted from the surface by the action of the eluents penetrating the silica pores.
Selectivity on YMC-Pack ODS-AQ can be subtly different from that seen on conventional ODS columns. Differences in selectivity are most often encountered when analyzing mixtures of relatively polar compounds. Typically, longer retention and greater resolution are observed with ODS-AQ. Available in both 120Å and 200Å pore sizes, YMC-Pack ODS-AQ is well-suited for analysis and purification of peptides and other biomolecules.

Specifications

General

Stationary Phase	YMC-Pack ODS-AQ (C18)
Pore Size	120 Å
Particle Size	5 µm
Column Length	250 mm
Column ID	4.6 mm

FAQs

Question: What is the column length of this aqueous-compatible ODS-AQ version?

Answer:250 mm, with a 4.6 mm inner diameter.

Question: What packing is installed in the longer ODS-AQ column?

Answer:5 µm, 120 Å C18 silica.

Question: Why use ODS-AQ for organic acids or nucleosides?

Answer:Its aqueous-compatible phase enables reversed-phase retention under strongly water-rich mobile-phase conditions.

Application Note

YMC-Pack ODS-AQ is an aqueous-compatible C18 reversed-phase analytical column using 5 µm silica particles with 120 Å pores. The longer 250 × 4.6 mm bed supports demanding separations of hydrophilic and moderately hydrophobic organic compounds using highly aqueous mobile phases. Its ODS-AQ surface is designed to maintain useful C18 retention under water-rich conditions, making it relevant to nucleosides, organic acids, glycosides and selected drug substances. Compared with the 150 mm ODS-AQ analytical column, this 250 mm format provides an extended separation path with different pressure and run-time requirements. It differs in selectivity and phase chemistry from ordinary fully endcapped ODS-A.

Ordering

Notice

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