Description
Key facts
CAS number:950912-80-8,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:410.3 Da,
Molecular formula:C19H22Cl2FN5,
PubChem:51049607,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:PF-670462,
Biological description:Potent, selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM for CK1ε and CK1δ, respectively). Shows >300-fold selectivity over CK2 and selectivity over more than 40 other kinases. Alters circadian rhythms in vivo.Also available in simple stock solutions (ab146728) - add 1 ml of water to get an exact, ready-to-use concentration.,
Canonical smiles:C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl,
InChi:InChI=1S/C19H20FN5.2ClH/c20-14-8-6-13(7-9-14)17-18(16-10-11-22-19(21)24-16)25(12-23-17)15-4-2-1-3-5-15;;/h6-12,15H,1-5H2,(H2,21,22,24);2*1H,
InChiKey:PSNKGVAXBSAHCH-UHFFFAOYSA-N,
IUPAC Name:4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
