Description
Key facts
CAS number:857064-38-1,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:356.2 Da,
Molecular formula:C17H14BrN3O,
PubChem:11210478,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM and in ethanol to 10 mM,
Biochemical name:(S,E)-3-(6-Bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide,
Biological description:JAK/STAT3 inhibitor (IC50 = 2.3 μM). More potent analog of AG 490 (ab120950). Antitumor activity in vitro and in vivo. Blood-brain barrier permeable.,
Canonical smiles:CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N,
Isomeric smiles:C[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N,
InChi:InChI=1S/C17H14BrN3O/c1-12(13-6-3-2-4-7-13)20-17(22)14(11-19)10-15-8-5-9-16(18)21-15/h2-10,12H,1H3,(H,20,22)/b14-10+/t12-/m0/s1,
InChiKey:VFUAJMPDXIRPKO-LQELWAHVSA-N,
IUPAC Name:(E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1809 WP1066. 1809-25 is the same size as the 25 mg size of ab141440.
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
