Description
Key facts
CAS number:1084893-56-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:431.5 Da,
Molecular formula:C24H29N7O,
PubChem:25211051,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 10 mM,
Biochemical name:(2S)-2-[[9-propan-2-yl-6-[[4-(2-pyridinyl)phenyl]methylamino]-2-purinyl]amino]-1-butanol,
Biological description:Potent, selective, cell-permeable cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor (IC50 = 41 - 400 nM). (R)-DRF053 (ab141505) analog. More potent than roscovirtine. Apoptosis inducer. GSK-3α/β (glycogen synthase kinase-3α/β) inhibitor. Antitumor potential.,
Canonical smiles:CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4,
Isomeric smiles:CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4,
InChi:InChI=1S/C24H29N7O/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(H2,26,28,29,30)/t19-/m0/s1,
InChiKey:HOCBJBNQIQQQGT-IBGZPJMESA-N,
IUPAC Name:(2S)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
