Key facts
Purity:>97%,
Form:SolidSee storage information,
Source:Axinella carteri,
Molecular weight:324.13 Da,
Molecular formula:C11H10BrN5O2,
PubChem:3035462,
Nature:Native,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:CID 3035462,
Biological description:Potent pan kinase inhibitor (IC50 values are 6, 10, 22, 28, 35, 40, 70, 80, 100, 470, 500, 600, 700 and 700 nM for MEK1, GSK-3β, Cdk1/cyclin B, Cdk5/p25, CK1, Cdk2/cyclin A, Cdk2/cyclin E, ASK-γ, Cdk3/cyclin E, Erk1, PKCγ, Cdk4/cyclin D1, Cdk6/cyclin D2 and PKCα respectively). Inhibits NF-κB and IL-8 production (IC50 values are 1-2 and 0.34-0.48 μM respectively, U937 cells). Inhibits MARK2.,
Canonical smiles:C1CNC(=O)C2=C(C1=C3C(=O)N=C(N3)N)C=C(N2)Br,
Isomeric smiles:C\1CNC(=O)C2=C(/C1=C\3/C(=O)N=C(N3)N)C=C(N2)Br,
InChi:InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4-,
InChiKey:ATBAETXFFCOZOY-DAXSKMNVSA-N,
IUPAC Name:(4Z)-4-(2-amino-4-oxo-1H-imidazol-5-ylidene)-2-bromo-1,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
