Description
Key facts
CAS number:511296-88-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:349.3 Da,
Molecular formula:C16H17BrN2S,
PubChem:11515812,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,
Biochemical name:Pifithrin-beta hydrobromide,
Biological description:Stable, cell-permeable analog of pifithrin-α (ab120478). Inhibits p53-mediated apoptosis and p53-dependent gene transcription. Prevents dexamethasone-induced cell death in murine thymocytes (EC50 = 2.01 μM). Potent STAT6 transcriptional inhibitor. Active in vivo and in vitro.See similar compound,
Canonical smiles:CC1=CC=C(C=C1)C2=CN3C4=C(CCCC4)SC3=N2.Br,
InChi:InChI=1S/C16H16N2S.BrH/c1-11-6-8-12(9-7-11)13-10-18-14-4-2-3-5-15(14)19-16(18)17-13;/h6-10H,2-5H2,1H3;1H,
InChiKey:SGNCOAOESGSEOP-UHFFFAOYSA-N,
IUPAC Name:2-(4-methylphenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole;hydrobromide
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
