Description
Key facts
CAS number:1357389-11-7,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:362.4 Da,
Molecular formula:C21H19FN4O,
PubChem:56650312,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide,
Biological description:Potent, selective HDAC3 inhibitor (IC50 = 80 nM). Induces DNA damage, impaired S phase progression and apoptosis in tumor cell lines. Shows central effects in vivo.,
Canonical smiles:C1=CC=C(C=C1)C=CCN2C=C(C=N2)C=CC(=O)NC3=C(C=C(C=C3)F)N,
Isomeric smiles:C1=CC=C(C=C1)/C=C/CN2C=C(C=N2)/C=C/C(=O)NC3=C(C=C(C=C3)F)N,
InChi:InChI=1S/C21H19FN4O/c22-18-9-10-20(19(23)13-18)25-21(27)11-8-17-14-24-26(15-17)12-4-7-16-5-2-1-3-6-16/h1-11,13-15H,12,23H2,(H,25,27)/b7-4+,11-8+,
InChiKey:BLVQHYHDYFTPDV-VCABWLAWSA-N,
IUPAC Name:(E)-N-(2-amino-4-fluorophenyl)-3-[1-[(E)-3-phenylprop-2-enyl]pyrazol-4-yl]prop-2-enamide
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions
