Description
Key facts
CAS number:220792-57-4,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:403.9 Da,
Molecular formula:C19H26ClN7O,
PubChem:6604931,
Nature:Synthetic,
Solubility:Soluble in ethanol to 50 mMSoluble in DMSO to 100 mM,
Biochemical name:aminopurvalanol A,
Biological description:Potent, cell-permeable cyclin-dependent kinase inhibitor (IC50 values are 33 (cdk1/cyclin B), 33 (cdk2/cyclin A), 28 (cdk2/cyclin E) and 20 nM (cdk5/p35)). Inhibits ERK1 (IC50 = 12.0 μM) and ERK2 (IC50 = 3.1 μM). Induces cell cycle arrest at G2/M phase (IC50 = 1.25 μM). Shows apoptotic effects.,
Canonical smiles:CC(C)C(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC(=C3)N)Cl,
Isomeric smiles:CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=CC(=C3)N)Cl,
InChi:InChI=1S/C19H26ClN7O/c1-10(2)15(8-28)24-19-25-17(23-14-6-12(20)5-13(21)7-14)16-18(26-19)27(9-22-16)11(3)4/h5-7,9-11,15,28H,8,21H2,1-4H3,(H2,23,24,25,26)/t15-/m0/s1,
InChiKey:RAMROQQYRRQPDL-HNNXBMFYSA-N,
IUPAC Name:(2R)-2-[[6-(3-amino-5-chloroanilino)-9-propan-2-ylpurin-2-yl]amino]-3-methylbutan-1-ol
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months
