Description
Key facts
CAS number:1254944-66-5,
Molecular weight:361.5 Da,
Molecular formula:C18H19NO3S2,
PubChem:53393127,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 25 mM,
Biochemical name:Ethyl 2-{[5-(methylsulfanyl)thiophen-2-yl]carbonyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylate,
Biological description:REV-ERBα antagonist (EC50 = 470 nM, REV-ERBα transcriptional repression activity). Stimulates the expression of gluconeogenesis genes G6Pase and PEPCK.,
Canonical smiles:CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC,
InChi:InChI=1S/C18H19NO3S2/c1-3-22-18(21)14-10-12-6-4-5-7-13(12)11-19(14)17(20)15-8-9-16(23-2)24-15/h4-9,14H,3,10-11H2,1-2H3,
InChiKey:UIEBLUZPSFAFOC-UHFFFAOYSA-N,
IUPAC Name:ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months
