Description
Key facts
CAS number:931398-72-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:352.3 Da,
Molecular formula:C19H16N2O5,
PubChem:54685215,
Nature:Synthetic,
Biochemical name:2-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid,
Biological description:Potent, cell-permeable, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3.,
Canonical smiles:C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O,
InChi:InChI=1S/C19H16N2O5/c22-15(23)10-20-18(25)16-17(24)13-8-4-5-9-14(13)21(19(16)26)11-12-6-2-1-3-7-12/h1-9,24H,10-11H2,(H,20,25)(H,22,23),
InChiKey:CAOSCCRYLYQBES-UHFFFAOYSA-N,
IUPAC Name:2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 9451 IOX2. 9451-25 is the same size as the 25 mg size of ab218604.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions
