Description
Key facts
CAS number:781661-94-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:443.3 Da,
Molecular formula:C20H19BrN4O3,
PubChem:11178236,
Nature:Synthetic,
Solubility:Soluble in DMSO to 55 mM,
Biochemical name:Sepantronium bromide,
Biological description:Novel small molecule potent survivin suppressant. Inhibits survivin promoter activity (IC50 = 0.54 nM) and down-regulates survivin in vitro and in vivo. Induces apoptosis in human tumor cell lines in vitro at 10 nM, with little effect on other IAP or Bcl-2 family members.,
Canonical smiles:CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-],
InChi:InChI=1S/C20H19N4O3.BrH/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25;/h3-8,11H,9-10,12H2,1-2H3;1H/q+1;/p-1,
InChiKey:QBIYUDDJPRGKNJ-UHFFFAOYSA-M,
IUPAC Name:1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione;bromide
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
