Description
Key facts
CAS number:1258861-20-9,
Form:SolidSee storage information,
Molecular weight:512.5 Da,
Molecular formula:C26H24F4N6O,
PubChem:49848070,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM with ultrasonic and warming,
Biochemical name:Taladegib,
Biological description:Potent Hedgehog signaling pathway inhibitor. Smoothened antagonist. Inhibits growth of cancer cell lines containing a disease-relevant Smoothened gene mutation. Has anti-tumor activity in animal models.,
Canonical smiles:CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F,
InChi:InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3,
InChiKey:SZBGQDXLNMELTB-UHFFFAOYSA-N,
IUPAC Name:4-fluoro-N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-2-(trifluoromethyl)benzamide
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
