Description
Key facts
CAS number:1351761-44-8,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:443.4 Da,
Molecular formula:C19H21F4N5O3,
PubChem:58539171,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM warming,
Biochemical name:[4-[[4-(Ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoro-5-methoxyphenyl]-morpholin-4-ylmethanone,
Biological description:Potent and selective, brain penetrant LRRK2 inhibitor (IC50 = 9 nM; Ki = 1nM). Tested against a panel of 187 kinases only one was inhibited >50% at 100 nM. Displays moderate 5-HT2B anatagonist activity in vitro.,
Canonical smiles:CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC,
InChi:InChI=1S/C19H21F4N5O3/c1-3-24-16-12(19(21,22)23)10-25-18(27-16)26-14-9-13(20)11(8-15(14)30-2)17(29)28-4-6-31-7-5-28/h8-10H,3-7H2,1-2H3,(H2,24,25,26,27),
InChiKey:XCFLWTZSJYBCPF-UHFFFAOYSA-N,
IUPAC Name:[4-[[4-(ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl]amino]-2-fluoro-5-methoxyphenyl]-morpholin-4-ylmethanone
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
