Description
Key facts
CAS number:1025065-69-3,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:405.4 Da,
Molecular formula:C20H22F3N5O,
PubChem:24795070,
Nature:Synthetic,
Solubility:?40.5 mg/mL in DMSO?101 mg/mL in EtOHInsoluble in H2O,
Biochemical name:N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine,
Biological description:Novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM, 50- and 10-fold selective versus Pim2 and Pim3. Preliminary results from studies treating prostate cancer cells.,
Canonical smiles:CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2,
InChi:InChI=1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26),
InChiKey:MHXGEROHKGDZGO-UHFFFAOYSA-N,
IUPAC Name:N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
