Description
Key facts
CAS number:1005342-46-0,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:500.6 Da,
Molecular formula:C26H33FN4O3S,
PubChem:24737642,
Nature:Synthetic,
Biochemical name:Lcl-161,
Biological description:Small molecule SMAC mimetic inhibitor of multiple IAP (Inhibitor of apoptosis) family proteins. (IC50 = 10.23 μM). Inhibits cell proliferation and viability in two human hepatocellular carcinoma cells (Hep3B, IC50 = 10, and PLC5, IC50 = 19).,
Canonical smiles:CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC,
Isomeric smiles:C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC,
InChi:InChI=1S/C26H33FN4O3S/c1-16(28-2)24(33)30-22(17-7-4-3-5-8-17)26(34)31-14-6-9-21(31)25-29-20(15-35-25)23(32)18-10-12-19(27)13-11-18/h10-13,15-17,21-22,28H,3-9,14H2,1-2H3,(H,30,33)/t16-,21-,22-/m0/s1,
InChiKey:UFPFGVNKHCLJJO-SSKFGXFMSA-N,
IUPAC Name:(2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide
Product details:
For obtaining a higher solubility, please warm the tube at 37°C and shake in the ultrasonic bath for a while.
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
