Description
Key facts
CAS number:1001264-89-6,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:458 Da,
Molecular formula:C24H32ClN5O2,
PubChem:24788740,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:Ipatasertib,
Biological description:Selective Akt1/2/3 inhibitor (IC50 = 5 nM, 18 nM and 8 nM, respectively). Selective for Akt over PKA (620-fold). ATP-competitive. Antitumor activity in vitro and in vivo.,
Canonical smiles:CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O,
Isomeric smiles:C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O,
InChi:InChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1,
InChiKey:GRZXWCHAXNAUHY-NSISKUIASA-N,
IUPAC Name:(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
