Description
Key facts
CAS number:1035072-16-2,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:477.4 Da,
Molecular formula:C23H22Cl2N2O3S,
PubChem:3689413,
Nature:Synthetic,
Solubility:Soluble in DMSO to >25 mM,
Biochemical name:2-[(chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide,
Biological description:ML-162 is a GPX4 (glutathione peroxidase 4) inhibitor that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC₅₀s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).,
Canonical smiles:COC1=C(C=C(C=C1)N(C(C2=CC=CS2)C(=O)NCCC3=CC=CC=C3)C(=O)CCl)Cl,
InChi:InChI=1S/C23H22Cl2N2O3S/c1-30-19-10-9-17(14-18(19)25)27(21(28)15-24)22(20-8-5-13-31-20)23(29)26-12-11-16-6-3-2-4-7-16/h2-10,13-14,22H,11-12,15H2,1H3,(H,26,29),
InChiKey:UNVKYJSNMVDZJE-UHFFFAOYSA-N,
IUPAC Name:2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N-(2-phenylethyl)-2-thiophen-2-ylacetamide
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2304 ML-162. B2304-5 is the same size as the 5 mg size of ab286999.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes
