Description
Key facts
CAS number:1253952-02-1,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:526.4 Da,
Molecular formula:C28H29Cl2N3O3,
PubChem:66599892,
Nature:Synthetic,
Solubility:Soluble in water to >25 mM,
Biochemical name:Netarsudil dihydrochloride,
Biological description:Netarsudil Hydrochloride (AR-13324) is a Rho kinase (ROCK) inhibitor with norepinephrine transport inhibitory activity that reduces production of aqueous humor. Netarsudil (AR-13324) is a potent, selective ROCK inhibitor with Ki of 4.2 nM for ROCK2; a novel ocular hypotensive agent for the treatment of glaucoma.,
Canonical smiles:CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)C(CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl,
Isomeric smiles:CC1=CC(=C(C=C1)C(=O)OCC2=CC=C(C=C2)[C@@H](CN)C(=O)NC3=CC4=C(C=C3)C=NC=C4)C.Cl.Cl,
InChi:InChI=1S/C28H27N3O3.2ClH/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;;/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H/t26-;;/m1../s1,
InChiKey:LDKTYVXXYUJVJM-FBHGDYMESA-N,
IUPAC Name:[4-[(2S)-3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl]phenyl]methyl 2,4-dimethylbenzoate;dihydrochloride
Product details:
This product is manufactured by BioVision, an Abcam company and was previously called B2387 Netarsudil dihydrochloride. B2387-5 is the same size as the 5 mg size of ab287030.
Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C
