Description
Product details
Patented technology Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
How are conjugated primary antibodies validated? This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling. For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on recombinant antibodies.
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
HOXB4 is essential in maintaining stem cell populations and directing hematopoietic stem cell differentiation. It does not form part of any large complex but it interacts with DNA to control the expression of specific genes critical for cellular development. By regulating these genes HOXB4 influences the proper formation of body structures during embryogenesis.
Pathways
HOXB4 is involved in the hematopoietic cell lineage and the anterior-posterior patterning pathway. It works alongside other Hox family proteins to establish the identity of cells and tissues along the body axis. A vital interaction exists with HOXA9 within these pathways which embodies collaborative control over blood cell formation and differentiation.