BD, 566345, Alexa Fluor® 647 Rat Anti-Mouse CD200R OX-110 (also known as OX110)

The OX-110 monoclonal antibody specifically binds to CD200R which is also known as OX2 receptor 1 (Ox2r) or MOX2 receptor (Mox2r). CD200R is a type I transmembrane glycoprotein that is encoded by Cd200r1 (CD200 receptor 1) and belongs to the C2-set domain containing gene family within the Ig superfamily. CD200R is expressed by hematopoietic cells including monocytes, granulocytes, and T cells. CD200R functions as an inhibitory receptor when bound by its ligand, CD200. CD200R signaling can inhibit leucocyte functions such as the production of cytokines.

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor® 647 under optimum conditions, and unreacted Alexa Fluor® 647 was removed.
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. An isotype control should be used at the same concentration as the antibody of interest.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. The Alexa Fluor®, Pacific Blue™, and Cascade Blue® dye antibody conjugates in this product are sold under license from Molecular Probes, Inc. for research use only, excluding use in combination with microarrays, or as analyte specific reagents. The Alexa Fluor® dyes (except for Alexa Fluor® 430), Pacific Blue™ dye, and Cascade Blue® dye are covered by pending and issued patents.
5. Alexa Fluor® is a registered trademark of Molecular Probes, Inc., Eugene, OR.
6. Alexa Fluor® 647 fluorochrome emission is collected at the same instrument settings as for allophycocyanin (APC).
7. For fluorochrome spectra and suitable instrument settings, please refer to our Multicolor Flow Cytometry web page at www.bdbiosciences.com/colors.
8. Please refer to www.bdbiosciences.com/us/s/resources for technical protocols.