Bio-Rad, 3710-0970, Diphtheria Toxin antibody

Goat anti diphtheria toxin antibody reacts with the diphtheria toxin/toxoid. Diphtheria toxin is an exotoxin secreted by various strains of Corynebacterium diphtheriae that is the cause of diphtheria. The active toxin is a single chain of 535 amino acids composed of 3 distinct structural/functional domains; and N-Terminal ADP-ribosyltransferase (catalytic domain); a region which facilitates the delivery of the catalytic domain across the cell membrane (transmembrane domain) and the eukaryotic cell receptor binding domain. Goat anti diphtheria toxin antibody also recognizes CRM 197 ( Conde et al. 2021), a non-toxic mutant form of diphtheria toxin with an amino acid substitution at glycine-52 to glutamic acid ( Giannini et al . 1984 ).

Storage Information
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.