Cytiva, 17020003, QAE Sephadex A-50, 5 kg

Cytiva QAE Sephadex A-50 in the 5 kg presentation supplies dry strong anion exchange resin for larger batch adsorption or packed-bed chromatography operations. Its cross-linked dextran matrix carries stable quaternary aminoethyl functional groups that bind negatively charged solutes under appropriate buffer conditions. The available capacity for a particular protein depends on molecular size, sample composition, operating pH and ionic strength. Hydrate and swell the resin completely before packing, and use a suitable column design or batch contact vessel for the desired process throughput. Buffer equilibration, sample clarification and salt-based elution development help maintain consistent separation performance across runs. The resin is supplied as dry material, so the packaged mass is not the final swollen bed volume. Work within the recommended pH range and assess cleaning conditions before reuse. The larger package supports repeated preparation of chromatography media while preserving the same separation principle as the smaller research pack.