Cytiva, 17371503, Capto adhere ImpRes, 1 L

Name: Capto adhere ImpRes, 1 L
Brand: Cytiva
SKU: 17371503

Catalog Number: 17371503

Pricing

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Category

Pre-Packed Flash Columns

Pack Size1 L

TagsChromatography resins Chromatography products Multimodal resins resin

CollectionsCytiva Chromatography Columns, Resins & Lab Glassware Cytiva Protein Analysis Equipment & Supplies Collection

Description

This multimodal, strong anion exchange resin supports effective mAb polishing in the second or third step of a purification scheme downstream of the protein A capture step.
High yields achieved through the high-resolution beads and selectivity of the ligand.
Efficient removal of aggregates, viruses, and main contaminants in mAb processes.
Enables use of a platform approach to mAb process development.
Allows separation of mAb charged variants.
Resin fulfills industrial demands for security of supply, robust performance, and regulatory support
Helps solve purification problems
The multimodal anion exchanger ligand of Capto adhere ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions.
The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.
Prepacked columns and other formats
Capto adhere ImpRes resin is available in the following formats:
Process development scale: prepacked
PreDictor Capto adhere ImpRes filter plates , 96-well plates for high-throughput screening or process development.
PreDictor Capto adhere ImpRes RoboColumn™ units , miniaturized columns for high-throughput process development.
HiScreen Capto adhere ImpRes columns , optimized for method and process development.
f (x) column , prepacked and precharacterized chromatography column for fast and accurate mechanistic modeling
Lab scale: prepacked for manual purification
HiTrap Capto adhere ImpRes columns , for easy use with a syringe, peristaltic pump, or chromatography system.
Lab scale: prepacked for automated purification and analysis
HiTrap Capto adhere ImpRes columns , for easy use with a syringe, peristaltic pump, or chromatography system.
Process characterization: resin kits
Process Characterization Kit Capto adhere ImpRes , designed for studying the potential impact that resin ligand density might have on the process outcome.
Process-scale purification: prepacked
ReadyToProcess Capto adhere ImpRes columns , 1 L and larger columns for clinical manufacturing that minimize the need for cleaning and cleaning validation.

Specifications

General

Avoid Using	Oxidizing agents, anionic detergents
Binding Capacity/ml Chromatography Medium	45-85 mg Mab/mL
BioProcess resin	Yes
Certificate of Analysis	Yes
Chemical stability	Commonly used aqueous buffers, 1 M acetic acid, 1 M NaOH, 2 M NaCl, 5% 1-propanol, 30% isopropanol, 70% ethanol
Ionic Capacity	0.08-0.11 mmol Cl - /ml medium
Ligand	Multimodal strong anion exchanger
Matrix	High-flow agarose
Particle size, d 50V	~40 μm
Pressure/Flow Specification	300 kPa
Storage	4°C to 30°C in 20% ethanol
pH stability, CIP	2–14
pH stability, operational	3–12

FAQs

Question: What is the pack size?

Answer:1 L of Capto adhere ImpRes bulk resin.

Question: What is the principal application?

Answer:High-resolution polishing of monoclonal antibodies and other proteins.

Question: Which type of chromatography does it support?

Answer:Multimodal anion exchange chromatography, including bind-and-elute polishing.

Application Note

Cytiva Capto adhere ImpRes is a multimodal strong anion exchange resin engineered for high-resolution separation of proteins and biopharmaceutical impurities. This 1 L bulk resin format supports chromatography column packing for method development, preparative purification and scale-up evaluation. A bead size of approximately 40 µm and a selective multimodal ligand enable polishing strategies that separate a target protein from product aggregates and other process-related components. Bind-and-elute operation can be used to recover antibody products through a controlled change in buffer conditions, while flow-through strategies can retain selected contaminants. The medium is particularly relevant after protein capture when additional purity is required. This format is supplied as bulk resin, so working column volume, bed height and process conditions are established during method design.

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

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