| Effective filtration area | 1.63 m² |
|---|---|
| Filter Format | 10 in. laid-over pleat filter cartridge |
| Membrane material | Hydrophilic modified polyvinylidenedifluoride (PVDF) |
| Removal ratings | T R 10 6 for 50 nm viruses |
Answer:Virus removal from suitable biopharmaceutical process streams as one step in a validated viral clearance strategy.
Answer:The AB-format cartridge has a nominal length of 10 inches.
Answer:No. It performs a different virus-retentive filtration function and requires process-specific validation.
The Pall Ultipor VF DV50 Virus Removal Filter Cartridge is a 10-inch filtration component designed for virus reduction during biopharmaceutical downstream processing. Its virus-retentive filter medium provides a dedicated barrier in a validated purification sequence, helping control adventitious viral contamination in suitable biological fluid streams. The DV50 format must be selected using process-specific virus clearance, flow capacity and product recovery studies rather than treated as an interchangeable conventional sterilizing-grade membrane. Feed composition, prefiltration, operating pressure and filter loading can influence process performance. Integrate the cartridge with correctly matched housings and sealing components, and verify assembly integrity before processing valuable material. Establish appropriate pre-use conditioning and post-use testing within the approved manufacturing procedure. A 10-inch cartridge is a filter element rather than a complete skid or housing, and it is not a replacement for a full viral safety strategy incorporating complementary clearance operations and qualified manufacturing controls.
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