Merck, 03-0187-00, SMC® Human MCP-1 High Sensitivity Immunoassay Kit

General description
Monocyte Chemoattractant Protein-1 (MCP-1), also known as CCL2, is a chemokine that plays a critical role in the recruitment of monocytes to sites of inflammation and injury. It is produced by various cell types, including macrophages, endothelial cells, and fibroblasts, in response to inflammatory stimuli. MCP-1 is involved in several physiological and pathological processes, including atherosclerosis, chronic inflammatory diseases, and tissue repair.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
Breakthrough-level sensitivity for translational research: Supports early-stage biomarker identification and immune profiling with unmatched precision.
Wide Quantification Range: Captures MCP-1 levels across both baseline and elevated inflammatory states, ideal for diverse sample types.
Streamlined ELISA Workflow with SMC® Enhancements: Uses a familiar sandwich immunoassay format with a unique elution step for digital molecule counting.
Illuminate Monocyte Migration Pathways: MCP-1 is a key chemokine in immune cell recruitment; this kit helps quantify its role in inflammation and tissue infiltration.

Packaging
96 well assay
Analysis Note
Sensitivity: LLOQ 150 fg/mL* (SMCxPRO® Instrument)
Standard Curve Range: 80-400,000 fg/mL
Intra-assay CV: Inter-assay CV: Linearity: Serum: 102% Plasma: 94%
Recovery: Serum: 104% Plasma: 101%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
MCP-1 was not cross-reactive with rat, mouse, or canine samples.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.