Merck, 03-0195-00, SMC® Human IL-2 High Sensitivity Immunoassay Kit

General description
Interleukin-2 (IL-2) is a crucial cytokine in the immune system, primarily produced by T cells. It plays a vital role in the proliferation, differentiation, and activation of immune cells, particularly T lymphocytes and natural killer (NK) cells. IL-2 is essential for maintaining immune homeostasis and is a key factor in the body′s response to infections and tumors.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
Breakthrough-Level Sensitivity For Translational Research: Supports early-stage biomarker identification and immune profiling with unmatched precision.
Support Autoimmune and Inflammatory Studies: Quantify IL-2 in models of autoimmunity, graft rejection, or chronic inflammation.
Illuminate Early Immune Activation: IL-2 is a key marker of T-cell activation; this assay helps detect it even at the earliest stages of immune response.
High Precision and Reproducibility: Verified across multiple operators and days, ensuring consistent, reliable results

Packaging
96 well assay
Analysis Note
Sensitivity: LLOQ 90 fg/mL* (SMCxPRO® Instrument)
Standard Curve Range: 20-80,000 fg/mL
Intra-assay CV: Inter-assay CV: Linearity: Serum: 108% Plasma: 104%
Recovery: Serum: 91% Plasma 83%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although IL-2 was detectable in non-human primate, canine, and feline samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.